Andrea Vuleta-Jensen of Jordan, Minn., jumped at the chance to take a full-time remote position in February 2021 as a project manager with MSP Communications in Minneapolis, a content marketer behind Mpls.St. Paul Magazine and Twin Cities Business.

For nine months, the arrangement went smoothly with Vuleta-Jensen working with graphic designers and writers from her basement — until an email mandating the COVID-19 vaccine arrived in her inbox last October.